Why are we hearing so much about CBD and skincare? It’s because our skin—the largest of our organs—contains a vast amount of cannabinoid receptors and endocannabinoid machinery. A number of excellent review papers1-3 show how endocannabinoids, along with the phytocannabinoids that work with them, affect everything from skin homeostasis and wound repair4 to skin permeability and the differentiation of skin stem cells.

We’ve seen increasing research on the endocannabinoid system (ECS) since it was discovered in the early 90s. The existence of the first two…